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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: SFRS1 All Species: 20.91
Human Site: S182 Identified Species: 35.38
UniProt: Q07955 Number Species: 13
    Phosphosite Substitution
    Charge Score: -0.31
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q07955 NP_001071634.1 248 27745 S182 L D N T K F R S H E G E T A Y
Chimpanzee Pan troglodytes Q5R1W5 221 25469 R156 S R S R T R S R S R S T S K S
Rhesus Macaque Macaca mulatta XP_001103473 406 44532 S335 L D N T K F R S H E G E T A Y
Dog Lupus familis XP_853057 292 32007 S182 L D N T K F R S H E F C L F N
Cat Felis silvestris
Mouse Mus musculus Q9D0B0 222 25643 R155 M G M V E Y L R K E D M E Y A
Rat Rattus norvegicus Q5PPI1 221 25480 R154 M G M V E Y L R K E D M E Y A
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001517964 202 22532 H137 D N T K F R S H E G E T A Y I
Chicken Gallus gallus Q5ZML3 257 28042 S182 L D N T K F R S H E G E T A Y
Frog Xenopus laevis NP_001088400 230 25898 I164 G M G I V E F I R K E D M E Y
Zebra Danio Brachydanio rerio Q6NYA0 245 27457 F179 R K L D N T K F R S H E G E T
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P26686 376 42795 R196 V E D R R G G R S G G G G G S
Honey Bee Apis mellifera XP_393525 248 28355 S183 L D D S R F R S H E G E V A Y
Nematode Worm Caenorhab. elegans Q9NEW6 258 28662 S184 L D D T K F R S H E G E T A Y
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana O22315 303 33711 V192 F S N G Y V R V R E Y D S R K
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 28.2 60.5 66.4 N.A. 64.1 64.1 N.A. 77 82 65.3 96.3 N.A. 23.6 68.5 60 N.A.
Protein Similarity: 100 37.9 60.8 72.5 N.A. 72.5 72.1 N.A. 78.2 85.9 76.2 97.5 N.A. 35.6 77.4 70.1 N.A.
P-Site Identity: 100 0 100 66.6 N.A. 6.6 6.6 N.A. 0 100 6.6 6.6 N.A. 6.6 73.3 93.3 N.A.
P-Site Similarity: 100 13.3 100 66.6 N.A. 26.6 26.6 N.A. 6.6 100 20 13.3 N.A. 33.3 93.3 100 N.A.
Percent
Protein Identity: N.A. N.A. N.A. 50.1 N.A. N.A.
Protein Similarity: N.A. N.A. N.A. 59 N.A. N.A.
P-Site Identity: N.A. N.A. N.A. 20 N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. 33.3 N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 0 0 0 0 0 0 8 36 15 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 8 0 0 0 % C
% Asp: 8 43 22 8 0 0 0 0 0 0 15 15 0 0 0 % D
% Glu: 0 8 0 0 15 8 0 0 8 65 15 43 15 15 0 % E
% Phe: 8 0 0 0 8 43 8 8 0 0 8 0 0 8 0 % F
% Gly: 8 15 8 8 0 8 8 0 0 15 43 8 15 8 0 % G
% His: 0 0 0 0 0 0 0 8 43 0 8 0 0 0 0 % H
% Ile: 0 0 0 8 0 0 0 8 0 0 0 0 0 0 8 % I
% Lys: 0 8 0 8 36 0 8 0 15 8 0 0 0 8 8 % K
% Leu: 43 0 8 0 0 0 15 0 0 0 0 0 8 0 0 % L
% Met: 15 8 15 0 0 0 0 0 0 0 0 15 8 0 0 % M
% Asn: 0 8 36 0 8 0 0 0 0 0 0 0 0 0 8 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 8 8 0 15 15 15 50 29 22 8 0 0 0 8 0 % R
% Ser: 8 8 8 8 0 0 15 43 15 8 8 0 15 0 15 % S
% Thr: 0 0 8 36 8 8 0 0 0 0 0 15 29 0 8 % T
% Val: 8 0 0 15 8 8 0 8 0 0 0 0 8 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 8 15 0 0 0 0 8 0 0 22 43 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _